DESCRIPTIVE INFORMATION BY DIAGNOSTIC MODEL

' M1 M2 M3
PEDIGREES WITH AN AFFECTED SIB-PAIR WITH DNA AVAILABLE      
# sibships, 2 affected sibs with DNA available 58 54 46
# sibships, 3 affected sibs with DNA available 40 35 16
# sibships, 4 affected sibs with DNA available 16 10 6
# sibships, 5 or more affected sibs with DNA available 8 4 1
Total # pedigrees,at least 1 affected sib-pair with DNA available 104 91 67
# affected sib-pairs with DNA available (n-1) 221 172 100
Maximum # affected sib-pairs with DNA available [n*(n-1)/2] 369 269 140
# affected sibs with DNA available 343 275 169
# other affected relatives with DNA available 95 74 50
Total # affecteds with DNA available 438 349 219
# unaffected sibs with DNA available 186 191 146
# other unaffected relatives with DNA available 348 330 285
Total # subjects with DNA available 972 870 650
# sibships, no parent with DNA available 13 11 5
# sibships, 1 parent with DNA available 34 29 21
# sibships, both parents with DNA available 75 63 43
# afffecteds with DNA available, by sex      
Female 135 116 69
Male 303 233 150
PEDIGREES WITHOUT AN AFFECTED SIB-PAIR WITH DNA AVAILABLE      
# pedigrees, one affected with DNA available 0 6 21
# pedigrees, 2 affecteds with DNA available 1 7 13
# pedigrees, 3 affecteds with DNA available 0 0 2
# pedigrees, 4 affecteds with DNA available 0 1 0
Total # pedigrees, at least 1 affected with DNA available 1 14 36
Total # affecteds with DNA available 2 24 53
Total # subjects with DNA available 7 109 329
TRIOS FOR ASSOCIATION ANALYSIS      
(AN AFFECTED INDIVIDUAL + 2 PARENTS WITH DNA AVAILABLE)      
# pedigrees containing at least 1 trio 73 73 65

MODEL 1: DSM-III-R + Feighner

MODEL 2: DSM-IV

MODEL 3: ICD-10

Last updated on 20Jan2000