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Genetic Data Distribution 2.0
Message from the NIAAA Director

Dear Colleague:

Alcoholism exacts a heavy toll on our society, not only on affected individuals and their families, but also through the lost workplace productivity, violence, traffic injuries and fatalities, and increased burden on our medical care system resulting directly or indirectly from the abuse of alcohol associated with alcoholism. In order to identify genes influencing susceptibility to this genetically complex disorder, the National Institute on Alcohol Abuse and Alcoholism (NIAAA) has supported the Collaborative Studies on Genetics of Alcoholism (COGA) since 1989.

The COGA investigators have mapped several loci linked to alcoholism at the suggestive level of statistical significance, and are currently attempting to identify the genes responsible for these linkage findings. (You will find a list of COGA’s publications elsewhere on this website.) COGA’s efforts have resulted in the creation of a set of clinical, diagnostic and genetic data and a repository of cell lines from more than three thousand members of families ascertained through a member affected with alcoholism. These data and cell lines should be a valuable resource for elucidating the genetics of alcoholism. NIAAA and the COGA investigators are pleased to make available to qualified investigators the clinical and genetic datafiles and the DNA samples and cell lines maintained by the COGA Distribution Centers.

We hope that your work with the NIAAA/COGA DNA samples and data will lead to future advances in our understanding of the biological bases of alcoholism, and help to alleviate the suffering of all those in our society whose lives have been impacted by this disease. For further information, please visit our website at http://www.niaaa.nih.gov.

T. K. Li, M.D.
Director

Last updated 03/13/2008